The epic story of the first contact, encounter, approach, betrayal and, eventually, life-transcending friendship, between Karamakate, an Amazonian shaman, last survivor of his people, and two scientists that, over the course of 40 years, travel through the Amazon in search of a sacred plant that can heal them. Inspired by the journals of the first explorers of the Colombian Amazon, Theodor Koch-Grunberg and Richard Evans Schultes.
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| Production | Marcelo Céspedes | Executive Producer |
| Production | César Rodríguez | Production Manager |
| Production | Raúl Bravo | Executive Producer |
| Production | Jose David Corredor | Production Coordinator |
| Production | Hori Mentasti | Executive Producer |
| Writing | Jacques Toulemonde | Writer |
| Editing | Etienne Boussac | Editor |
| Art | Angélica Perea | Production Design |
| Writing | Ciro Guerra | Writer |
| Directing | Ciro Guerra | Director |
| Production | Gustavo Moyano | Casting |
| Costume & Make-Up | Catherine Rodríguez | Costume Design |
| Camera | David Gallego | Director of Photography |
| Art | Alejandro Franco | Set Decoration |
| Production | Cristina Gallego | Producer |
| Production | Esteban Mentasti | Co-Producer |
| Art | Angélica Perea | Art Direction |
| Art | Ramses Benjumea | Art Direction |
| Sound | Nascuy Linares | Original Music Composer |
| Editing | Marco Salaverría | Dialogue Editor |
| Sound | Carlos García | Sound Designer |
| Sound | Nerina Valido | Foley |
| Crew | Marco Salaverría | Sound Recordist |
| Camera | Huver González | First Assistant Camera |
| Sound | Carlos García | Supervising Sound Editor |
| Camera | Andres Cordoba | Still Photographer |
| Costume & Make-Up | Ana María Jauregui | Makeup Artist |
| Art | Alirio Cruz | Assistant Art Director |
| Camera | Andrés Barrientos | Still Photographer |
| Camera | Liliana Merizalde | Still Photographer |
| Lighting | Giovanni Barrios | Gaffer |
| Costume & Make-Up | Geraldine Vargas | Assistant Costume Designer |
| Crew | Andre Gains | Thanks |
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